GROWING UP IN IRELAND. Cohort '08 (Infant Cohort). Design, Instrumentation and Procedures for Cohort ’08 of Growing Up in Ireland at 9 Years Old (Wave 5)

Growing Up in Ireland is the national longitudinal cohort study of children that commenced in 2006. The study has followed two groups of Irish children: Cohort ’98 (so-called because most of them were born in 1998; formerly called the ‘Child Cohort’); and Cohort ’08 (most of whom were born a decade later in 2008; formerly called the ‘Infant Cohort’). The primary aim of the study is to provide a strong evidence base to improve the understanding of children’s and young people’s health and development across a range of domains. This information is used to inform government policy in relation to children, yong people and their families

Growing up in Ireland. National Longitudinal Study of Children. Report 9 2019

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Growing up in Ireland: The lives of 17/18-Year-olds of Cohort ’98 (Child Cohort). ESRI Growing Up in Ireland Report July 2020.

New Growing Up in Ireland research paints a picture of the lives of 17/18-year-olds in 2016: generally in good health and ambitious for their futures, but with inequalities persisting

Growing Up in Ireland: Key findings from the special COVID-19 survey of Cohorts ’98 and ‘08. ESRI Growing Up in Ireland March 2021.

In a new short report released today, the ESRI and Trinity College Dublin launch the results of a special survey of COVID-19 experiences for children and young adults participating in Growing Up in Ireland. These first insights highlight the extent of changes to everyday life as a result of the pandemic and point to likely inequalities in impact

Growing Up in Ireland: Growing up and developing as an adult: A review of the literature on selected topics pertaining to cohort ’98 at age 20 years. ESRI Report December 2020.

The goal of this report is to provide research information on selected potential research questions using data collected in interviews with 20-year-olds and their parents. At the time of writing, fieldwork was under way, so the topics of the survey were known but not the outcome of the interviews. The research questions address the central outcomes of the Growing Up in Ireland study that contribute to building developmental trajectories from childhood to adulthood: socio-emotional well-being; educational and cognitive development; physical health and growth. Three potential research questions are outlined under each outcome and provide a short supporting review of the national and international literature, followed by a description of the measures in Growing Up in Ireland useful in exploring the topic. While there is a wide array of possible research questions with a dataset such as this, the selected topics are those that offer new potential given the measures at this particular wave and/or are particularly salient to this phase of the life-course

Design, instrumentation and procedures for Cohort ‘08 of Growing Up in Ireland at 9 years old (Wave 5).

Growing Up in Ireland is the national longitudinal cohort study of children that commenced in 2006. The study has followed two groups of Irish children: Cohort ’98 (so-called because most of them were born in 1998; formerly called the ‘Child Cohort’); and Cohort ’08 (most of whom were born a decade later in 2008; formerly called the ‘Infant Cohort’). The primary aim of the study is to provide a strong evidence base to improve the understanding of children’s and young people’s health and development across a range of domains. This information is used to inform government policy in relation to children, young people and their families. This report gives details of the data collection and research methods used. The study covers a broad range of child outcomes with a view to documenting how well children and young people in Ireland are developing. In so doing, it can facilitate comparison with findings from similar studies of children in other countries, as well as establishing typical patterns for children in Ireland. Being longitudinal in nature, the study also addresses developmental trajectories over time and explores the factors that most affect those trajectories and the life chances of children in Ireland today. By providing comprehensive data on a representative national sample of Irish children, the study informs and contributes to the setting of responsive policies and the design of services for children and their families

Growing Up in Ireland: The lives of 9-year-olds of cohort '08. ESRI Growing up in Ireland June 2021.

This report provides a descriptive analysis of the findings from detailed interviews conducted between June 2017 and April 2018 with 8,032 9-year-olds and their families from Cohort ’08 (formerly known as the Infant Cohort) of the Growing Up in Ireland study. These families were first interviewed when the Study Child was 9 months old (September 2008 to March 2009) and followed up at 3 years of age (January-August 2011) and 5 years of age (March-September 2013). An inter-wave postal survey was conducted when the cohort was 7/8 years of age (March-October 2016). Responses at 9 years of age represented 72 per cent of the original sample interviewed at Wave 1. The data have been re-weighted to account for differential response across different groups. Capturing experiences and outcomes in middle childhood is crucial as peers become more important in children’s lives and they take a more active role in shaping the nature of their play and activities. Middle childhood is also an important period for developing social and cognitive skills and for children’s emerging self-concept. Behaviours at this stage, including physical activity and diet, may have longer-term consequences for physical health and well-being

Birth delivery method affects expression of immune genes in lung and jejunum tissue of neonatal beef calves

peer-reviewedBackground Caesarean section is a routine veterinary obstetrical procedure employed to alleviate dystocia in cattle. However, CS, particularly before the onset of labour, is known to negatively affect neonatal respiration and metabolic adaptation in humans, though there is little published information for cattle. The aim of this study was to investigate the effect of elective caesarean section (ECS) or normal trans-vaginal (TV) delivery, on lung and jejunal gene expression profiles of neonatal calves. Results Paternal half-sib Angus calves (gestation length 278 + 1.8 d) were delivered either transvaginally (TV; n = 8) or by elective caesarean section (ECS; n = 9) and immediately euthanized. Lung and jejunum epithelial tissue was isolated and snap frozen. Total RNA was extracted using Trizol reagent and reverse transcribed to generate cDNA. For lung tissue, primers were designed to target genes involved in immunity, surfactant production, cellular detoxification, membrane transport and mucin production. Primers for jejunum tissue were chosen to target mucin production, immunoglobulin uptake, cortisol reaction and membrane trafficking. Quantitative real-time PCR reactions were performed and data were statistically analysed using mixed models ANOVA. In lung tissue the expression of five genes were affected (p < 0.05) by delivery method. Four of these genes were present at lower (LAP, CYP1A1, SCN11α and SCN11β) and one (MUC5AC) at higher abundance in ECS compared with TV calves. In jejunal tissue, expression of TNFα, Il-1β and 1 l-6 was higher in ECS compared with TV calves. Conclusions This novel study shows that ECS delivery affects the expression of key genes involved in the efficiency of the pulmonary liquid to air transition at birth, and may lead to an increased inflammatory response in jejunal tissue, which could compromise colostral immunoglobulin absorption. These findings are important to our understanding of the viability and management of neonatal calves born through ECS